WHO / HEALTH EMERGENCIES
29-Mar-2023
00:04:37
A World Health Organization committee has reviewed the evidence for four Marburg vaccines. WHO
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STORY: WHO / HEALTH EMERGENCIES
TRT: 04:37
SOURCE: WHO
RESTRICTIONS: NONE
LANGUAGE: ENGLISH / NATS
DATELINE: 29 MARCH 2023, GENEVA, SWITZERLAND
TRT: 04:37
SOURCE: WHO
RESTRICTIONS: NONE
LANGUAGE: ENGLISH / NATS
DATELINE: 29 MARCH 2023, GENEVA, SWITZERLAND
SHOTLIST
1. Med shot, WHO entrance
2. Wide shot, press briefing room
3. SOUNDBITE (English) Dr. Tedros Adhanom Ghebreyesus, Director-General, World Health Organization (WHO):
“First to the outbreaks of Marburg virus disease in Equatorial Guinea and Tanzania. In Equatorial Guinea, WHO is on the ground with partners, supporting the Ministry of Health to respond to the outbreak. We have deployed teams to assist with case finding, clinical care, logistics, and community engagement. We have also helped to establish treatment units in the affected areas. The number of officially reported cases remains at nine, with seven deaths, in three provinces. However, these three provinces are 150 kilometers apart, suggesting wider transmission of the virus. WHO is aware of additional cases, and we have asked the government to report these cases officially to WHO.”
4. Wide shot, press briefing room
5. SOUNDBITE (English) Dr. Tedros Adhanom Ghebreyesus, Director-General, World Health Organization (WHO):
“In Tanzania, the number of confirmed cases remains at 8, with 5 deaths. Three people are currently being treated in a health facility. Two health workers are among the confirmed cases, including one death. So far, all of the reported cases are in one region. WHO and partners, including UNICEF, the US CDC, and MSF, have offered support to the government to bridge any gaps in the response.”
6. Wide shot, press briefing room
7. SOUNDBITE (English) Dr. Tedros Adhanom Ghebreyesus, Director-General, World Health Organization (WHO):
“WHO is working to begin trials of vaccines and therapeutics as soon as possible. A WHO committee has now reviewed the evidence for four vaccines. Trial protocols are ready, and our partners are ready to support the trials. We look forward to working with the governments of both countries to begin these trials, to help prevent cases and deaths now and in future outbreaks.”
8. Wide shot, press briefing room
9. SOUNDBITE (English) Dr. Ana Maria Henao Restrepo, Co-Lead, Research and Development Blueprint, World Health Organization (WHO):
“What we are talking about is this phrase three ring vaccination trial. It means we will offer the vaccine to the contacts, close contacts of the cases. And this is in our experience; this is about 20-50 people, depend on the social network of each case.”
10. Wide shot, press briefing room
11. SOUNDBITE (English) Dr. Ana Maria Henao Restrepo, Co-Lead, Research and Development Blueprint, World Health Organization (WHO):
“We don't need thousands of doses because it is not a population-level vaccination, but our experience suggests that vaccinating around the context of each case, there is a handful of people at higher risk, it is possible to document whether or not the vaccines are effective and to contribute to stop transmission with the other measures.”
12. Wide shot, press briefing room
13. SOUNDBITE (English) Dr. Rahman Mahamud, Director a.i., Alert & Response Coordination Dept, World Health Organization (WHO):
“In Burundi, we are aware of nine alerts, and three of them have been already dead, and the samples were taken, initial samples taken when they were alive showed negative for Marburg for ebola and dengue, but the team is working closely with our regional office, sending that sample to the neighbouring country Uganda and to the WHO regional office, regional collaboration centre for further confirmation.”
14. Wide shot, press briefing room
15. SOUNDBITE (English) Dr. Rahman Mahamud, Director a.i., Alert & Response Coordination Dept, World Health Organization (WHO):
“And until we have confirmation from the UVRI lab in Uganda and the WHO collaboration centres, all diagnoses are still in play, so establishing contact tracing, community engagement, all the pillars of the response need to be strengthened in all the countries neighbouring Tanzania.”
16. Wide shot, press briefing room
17. SOUNDBITE (English) Dr. Maria Van Kerkhove, COVID-19 Technical lead, Health Emergencies Programme, World Health Organization (WHO):
“At the present time, we are still in a Public Health Emergency of International Concern at a global level as well as still in a pandemic. The virus is circulating. We are in a much better situation than we were since the beginning of this pandemic. While we still see a lot of circulation of the virus, we are not seeing the same level of impact. And by impact, we mean there are reduced incidents of hospitalization, ICU, and death, but the threat isn’t over.”
18. Wide shot, press briefing room
19. SOUNDBITE (English) Dr. Maria Van Kerkhove, COVID-19 Technical lead, Health Emergencies Programme, World Health Organization (WHO):
“One of the things we are very concerned about is the potential for the virus to change, to become more, not only more transmissible but more severe. And so, we have to remain vigilant. We have to have systems that are in place which have strong surveillance so we can track the known variants in circulation, detect new ones so we can have agile systems to scale up or scale down the need for clinical care. Making sure that we have good antivirals that are in use and given to patients who need them, when they need them, to prevent severe disease and really critically to focus on vaccinating those who are most at risk.”
20. Wide shot, press briefing room
2. Wide shot, press briefing room
3. SOUNDBITE (English) Dr. Tedros Adhanom Ghebreyesus, Director-General, World Health Organization (WHO):
“First to the outbreaks of Marburg virus disease in Equatorial Guinea and Tanzania. In Equatorial Guinea, WHO is on the ground with partners, supporting the Ministry of Health to respond to the outbreak. We have deployed teams to assist with case finding, clinical care, logistics, and community engagement. We have also helped to establish treatment units in the affected areas. The number of officially reported cases remains at nine, with seven deaths, in three provinces. However, these three provinces are 150 kilometers apart, suggesting wider transmission of the virus. WHO is aware of additional cases, and we have asked the government to report these cases officially to WHO.”
4. Wide shot, press briefing room
5. SOUNDBITE (English) Dr. Tedros Adhanom Ghebreyesus, Director-General, World Health Organization (WHO):
“In Tanzania, the number of confirmed cases remains at 8, with 5 deaths. Three people are currently being treated in a health facility. Two health workers are among the confirmed cases, including one death. So far, all of the reported cases are in one region. WHO and partners, including UNICEF, the US CDC, and MSF, have offered support to the government to bridge any gaps in the response.”
6. Wide shot, press briefing room
7. SOUNDBITE (English) Dr. Tedros Adhanom Ghebreyesus, Director-General, World Health Organization (WHO):
“WHO is working to begin trials of vaccines and therapeutics as soon as possible. A WHO committee has now reviewed the evidence for four vaccines. Trial protocols are ready, and our partners are ready to support the trials. We look forward to working with the governments of both countries to begin these trials, to help prevent cases and deaths now and in future outbreaks.”
8. Wide shot, press briefing room
9. SOUNDBITE (English) Dr. Ana Maria Henao Restrepo, Co-Lead, Research and Development Blueprint, World Health Organization (WHO):
“What we are talking about is this phrase three ring vaccination trial. It means we will offer the vaccine to the contacts, close contacts of the cases. And this is in our experience; this is about 20-50 people, depend on the social network of each case.”
10. Wide shot, press briefing room
11. SOUNDBITE (English) Dr. Ana Maria Henao Restrepo, Co-Lead, Research and Development Blueprint, World Health Organization (WHO):
“We don't need thousands of doses because it is not a population-level vaccination, but our experience suggests that vaccinating around the context of each case, there is a handful of people at higher risk, it is possible to document whether or not the vaccines are effective and to contribute to stop transmission with the other measures.”
12. Wide shot, press briefing room
13. SOUNDBITE (English) Dr. Rahman Mahamud, Director a.i., Alert & Response Coordination Dept, World Health Organization (WHO):
“In Burundi, we are aware of nine alerts, and three of them have been already dead, and the samples were taken, initial samples taken when they were alive showed negative for Marburg for ebola and dengue, but the team is working closely with our regional office, sending that sample to the neighbouring country Uganda and to the WHO regional office, regional collaboration centre for further confirmation.”
14. Wide shot, press briefing room
15. SOUNDBITE (English) Dr. Rahman Mahamud, Director a.i., Alert & Response Coordination Dept, World Health Organization (WHO):
“And until we have confirmation from the UVRI lab in Uganda and the WHO collaboration centres, all diagnoses are still in play, so establishing contact tracing, community engagement, all the pillars of the response need to be strengthened in all the countries neighbouring Tanzania.”
16. Wide shot, press briefing room
17. SOUNDBITE (English) Dr. Maria Van Kerkhove, COVID-19 Technical lead, Health Emergencies Programme, World Health Organization (WHO):
“At the present time, we are still in a Public Health Emergency of International Concern at a global level as well as still in a pandemic. The virus is circulating. We are in a much better situation than we were since the beginning of this pandemic. While we still see a lot of circulation of the virus, we are not seeing the same level of impact. And by impact, we mean there are reduced incidents of hospitalization, ICU, and death, but the threat isn’t over.”
18. Wide shot, press briefing room
19. SOUNDBITE (English) Dr. Maria Van Kerkhove, COVID-19 Technical lead, Health Emergencies Programme, World Health Organization (WHO):
“One of the things we are very concerned about is the potential for the virus to change, to become more, not only more transmissible but more severe. And so, we have to remain vigilant. We have to have systems that are in place which have strong surveillance so we can track the known variants in circulation, detect new ones so we can have agile systems to scale up or scale down the need for clinical care. Making sure that we have good antivirals that are in use and given to patients who need them, when they need them, to prevent severe disease and really critically to focus on vaccinating those who are most at risk.”
20. Wide shot, press briefing room
STORYLINE
A World Health Organization (WHO) committee has reviewed the evidence for four Marburg vaccines.
Briefing journalists in Geneva today (29 Mar), Dr. Tedros Adhanom Ghebreyesus, WHO Director-General, said that in Equatorial Guinea, his agency is on the ground with partners, supporting the Ministry of Health to respond to the outbreak of Marburg virus disease.
He continued, “We have deployed teams to assist with case finding, clinical care, logistics, and community engagement. We have also helped to establish treatment units in the affected areas. The number of officially reported cases remains at nine, with seven deaths, in three provinces. However, these three provinces are 150 kilometers apart, suggesting wider transmission of the virus. WHO is aware of additional cases, and we have asked the government to report these cases officially to WHO.
In Tanzania, Tedros said that the number of confirmed cases remains at 8, with 5 deaths.
Three people are currently being treated in a health facility.
Two health workers are among the confirmed cases, including one death. So far, all of the reported cases are in one region.
WHO and partners, including UNICEF, the US CDC, and MSF, have offered support to the government to bridge any gaps in the response.
Tedros also said, “WHO is working to begin trials of vaccines and therapeutics as soon as possible. A WHO committee has now reviewed the evidence for four vaccines. Trial protocols are ready, and our partners are ready to support the trials. We look forward to working with the governments of both countries to begin these trials, to help prevent cases and deaths now and in future outbreaks.”
Dr. Ana Maria Henao Restrepo, WHO’s Co-Lead of Research and Development Blueprint, explained, “What we are talking about is this phrase three ring vaccination trial. It means we will offer the vaccine to the contacts, close contacts of the cases. And this is in our experience; this is about 20-50 people, depend on the social network of each case.”
She also said, “We don't need thousands of doses because it is not a population-level vaccination, but our experience suggests that vaccinating around the context of each case, there is a handful of people at higher risk, it is possible to document whether or not the vaccines are effective and to contribute to stop transmission with the other measures.”
Dr. Abdi Rahman Mahamud, WHO Director (a.i.) of the Alert & Response Coordination Department, said, “In Burundi, we are aware of nine alerts, and three of them have been already dead, and the samples were taken, initial samples taken when they were alive showed negative for Marburg for ebola and dengue, but the team is working closely with our regional office, sending that sample to the neighbouring country Uganda and to the WHO regional office, regional collaboration centre for further confirmation.”
He also said, “until we have confirmation from the UVRI lab in Uganda and the WHO collaboration centres, all diagnoses are still in play, so establishing contact tracing, community engagement, all the pillars of the response need to be strengthened in all the countries neighbouring Tanzania.”
Dr. Maria Van Kerkhove, Technical Lead Covid-19 of WHO Health Emergencies Programme, said, “At the present time, we are still in a Public Health Emergency of International Concern at a global level as well as still in a pandemic. The virus is circulating. We are in a much better situation than we were since the beginning of this pandemic. While we still see a lot of circulation of the virus, we are not seeing the same level of impact. And by impact, we mean there are reduced incidents of hospitalization, ICU, and death, but the threat isn’t over.”
She also said, “One of the things we are very concerned about is the potential for the virus to change, to become more, not only more transmissible but more severe. And so we have to remain vigilant. We have to have systems that are in place which have strong surveillance so we can track the known variants in circulation, detect new ones so we can have agile systems to scale up or scale down the need for clinical care. Making sure that we have good antivirals that are in use and given to patients who need them, when they need them, to prevent severe disease and really critically to focus on vaccinating those who are most at risk.”
Briefing journalists in Geneva today (29 Mar), Dr. Tedros Adhanom Ghebreyesus, WHO Director-General, said that in Equatorial Guinea, his agency is on the ground with partners, supporting the Ministry of Health to respond to the outbreak of Marburg virus disease.
He continued, “We have deployed teams to assist with case finding, clinical care, logistics, and community engagement. We have also helped to establish treatment units in the affected areas. The number of officially reported cases remains at nine, with seven deaths, in three provinces. However, these three provinces are 150 kilometers apart, suggesting wider transmission of the virus. WHO is aware of additional cases, and we have asked the government to report these cases officially to WHO.
In Tanzania, Tedros said that the number of confirmed cases remains at 8, with 5 deaths.
Three people are currently being treated in a health facility.
Two health workers are among the confirmed cases, including one death. So far, all of the reported cases are in one region.
WHO and partners, including UNICEF, the US CDC, and MSF, have offered support to the government to bridge any gaps in the response.
Tedros also said, “WHO is working to begin trials of vaccines and therapeutics as soon as possible. A WHO committee has now reviewed the evidence for four vaccines. Trial protocols are ready, and our partners are ready to support the trials. We look forward to working with the governments of both countries to begin these trials, to help prevent cases and deaths now and in future outbreaks.”
Dr. Ana Maria Henao Restrepo, WHO’s Co-Lead of Research and Development Blueprint, explained, “What we are talking about is this phrase three ring vaccination trial. It means we will offer the vaccine to the contacts, close contacts of the cases. And this is in our experience; this is about 20-50 people, depend on the social network of each case.”
She also said, “We don't need thousands of doses because it is not a population-level vaccination, but our experience suggests that vaccinating around the context of each case, there is a handful of people at higher risk, it is possible to document whether or not the vaccines are effective and to contribute to stop transmission with the other measures.”
Dr. Abdi Rahman Mahamud, WHO Director (a.i.) of the Alert & Response Coordination Department, said, “In Burundi, we are aware of nine alerts, and three of them have been already dead, and the samples were taken, initial samples taken when they were alive showed negative for Marburg for ebola and dengue, but the team is working closely with our regional office, sending that sample to the neighbouring country Uganda and to the WHO regional office, regional collaboration centre for further confirmation.”
He also said, “until we have confirmation from the UVRI lab in Uganda and the WHO collaboration centres, all diagnoses are still in play, so establishing contact tracing, community engagement, all the pillars of the response need to be strengthened in all the countries neighbouring Tanzania.”
Dr. Maria Van Kerkhove, Technical Lead Covid-19 of WHO Health Emergencies Programme, said, “At the present time, we are still in a Public Health Emergency of International Concern at a global level as well as still in a pandemic. The virus is circulating. We are in a much better situation than we were since the beginning of this pandemic. While we still see a lot of circulation of the virus, we are not seeing the same level of impact. And by impact, we mean there are reduced incidents of hospitalization, ICU, and death, but the threat isn’t over.”
She also said, “One of the things we are very concerned about is the potential for the virus to change, to become more, not only more transmissible but more severe. And so we have to remain vigilant. We have to have systems that are in place which have strong surveillance so we can track the known variants in circulation, detect new ones so we can have agile systems to scale up or scale down the need for clinical care. Making sure that we have good antivirals that are in use and given to patients who need them, when they need them, to prevent severe disease and really critically to focus on vaccinating those who are most at risk.”
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