WHO / CANCER REPORT

12-Sep-2018 00:03:06
The International Agency for Research on Cancer (IARC) today released the latest estimates on the global burden of cancer which is said to have risen to 18.1 million new cases and 9.6 million deaths in 2018, with one in five men and one in six women worldwide develop cancer during their lifetime, and one in eight men and one in eleven women die from the disease. WHO
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STORY: WHO / CANCER REPORT
TRT: 3:06
SOURCE: WHO
RESTRICTIONS: NONE
LANGUAGE: ENGLISH /NATS

DATELINE: 12 SEPTEMBER 2018, GENEVA, SWITZERLAND
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FILE

1. Aerial shot, exterior, WHO Building

12 SEPTEMBER 2018, GENEVA, SWITZERLAND

2. Wide shot, Wild and Krug preparing for interview
3. SOUNDBITE (English) Dr Christopher Wild, Director, The International Agency for Research on Cancer (IARC):
"The main findings from this new analysis which is for 2018, it is across over 185 countries, is that we estimate 18.1 million new cases per year occurring across the world and 9.6 million deaths. So, this translates through now to one in five men developing a cancer in their lifetime and one in six women. And I think one of the striking observations is the way that the aging of the population and the growth of the populations, particularly in certain parts of the world, is driving that rise in the total number of cases and unfortunately total number people dying from the disease."
4. Cutaway, Wild with reporter
5. SOUNDBITE (English) Dr Christopher Wild, Director, The International Agency for Research on Cancer (IARC):
"I think one of the things that struck me the most when I looked at this new set of figures is the way that breast cancer has become the most common cancer amongst women, in the majority of countries now worldwide, even in regions such as sub-Saharan Africa where traditionally it’s not been as common for example as cervical cancer. So this is really changing the pattern of the cancer burden, by region and in turn it should drive some of the planning in terms of cancer control priorities in those regions."
6. Wide shot, Krug and reporter
7. SOUNDBITE (English) Dr Etienne Krug, Director, Department of Noncommunicable Diseases, Disability, Violence and Injury Prevention, WHO:
"These new numbers should be a call to action, they show we have an increasingly large public health crisis with cancer growing in almost all parts of the world even in the poorest countries where traditionally infectious diseases were the dominating burden of disease. It shouldn't be like that, there’s a lot that can be done in terms of prevention; tackling tobacco consumption, reducing alcohol consumption, increasing physical activity, vaccination against some types of cancers. As well as strengthening health systems, so that they be better prepared to detect cancers early, facilitate treatment, increase and improve access to medicines and when needed have palliative care."
8. Wide shot, Krug and reporter
9. SOUNDBITE (English) Dr Etienne Krug, Director, Department of Noncommunicable Diseases, Disability, Violence and Injury Prevention, WHO:
"WHO is scaling up its response to cancer, the Director-General just announced an initiative to eliminate cervical cancer which can be done through vaccination as well as improved detection and treatment. We’re also working to scale up our response to childhood cancer, we are supporting countries in cancer registries and national plans. We are advocating for more attention and we are preparing for the high-level meeting on noncommunicable diseases, which will take place in New York on the 27th September, talking about cancer but also about cardio vascular disease, diabetes and respiratory diseases and basically calling on heads of states to take on a leading role to tackle what is the most prominent public health problem of this century."
10. Wide shot, Krug and Wild talking
STORYLINE
The International Agency for Research on Cancer (IARC) today released the latest estimates on the global burden of cancer which is said to have risen to 18.1 million new cases and 9.6 million deaths in 2018, with one in five men and one in six women worldwide develop cancer during their lifetime, and one in eight men and one in eleven women die from the disease.

The GLOBOCAN 2018 database, accessible online as part of the IARC Global Cancer Observatory, provides estimates of incidence and mortality in 185 countries for 36 types of cancer and for all cancer sites combined. An analysis of these results, published Wednesday (12 Sep) in CA: A Cancer Journal for Clinicians, highlights the large geographical diversity in cancer occurrence and the variations in the magnitude and profile of the disease between and within world regions.

SOUNDBITE (English) Dr Christopher Wild, Director, The International Agency for Research on Cancer (IARC):
"The main findings from this new analysis which is for 2018, it is across over 185 countries, is that we estimate 18.1 million new cases per year occurring across the world and 9.6 million deaths. So, this translates through now to one in five men developing a cancer in their lifetime and one in six women. And I think one of the striking observations is the way that the aging of the population and the growth of the populations, particularly in certain parts of the world, is driving that rise in the total number of cases and unfortunately total number people dying from the disease."

Worldwide, the total number of people who are alive within five years of a cancer diagnosis, called the five-year prevalence, is estimated to be 43.8 million.

SOUNDBITE (English) Dr Christopher Wild, Director, The International Agency for Research on Cancer (IARC):
"I think one of the things that struck me the most when I looked at this new set of figures is the way that breast cancer has become the most common cancer amongst women, in the majority of countries now worldwide, even in regions such as sub-Saharan Africa where traditionally it’s not been as common for example as cervical cancer. So this is really changing the pattern of the cancer burden, by region and in turn it should drive some of the planning in terms of cancer control priorities in those regions."

The increasing cancer burden is due to several factors, including population growth and ageing as well as the changing prevalence of certain causes of cancer linked to social and economic development. This is particularly true in rapidly growing economies, where a shift is observed from cancers related to poverty and infections to cancers associated with lifestyles more typical of industrialized countries.

SOUNDBITE (English) Dr Etienne Krug, Director, Department of Noncommunicable Diseases, Disability, Violence and Injury Prevention, WHO:
"These new numbers should be a call to action, they show we have an increasingly large public health crisis with cancer growing in almost all parts of the world even in the poorest countries where traditionally infectious diseases were the dominating burden of disease. It shouldn't be like that, there’s a lot that can be done in terms of prevention; tackling tobacco consumption, reducing alcohol consumption, increasing physical activity, vaccination against some types of cancers. As well as strengthening health systems, so that they be better prepared to detect cancers early, facilitate treatment, increase and improve access to medicines and when needed have palliative care."

Effective prevention efforts may explain the observed decrease in incidence rates for some cancers, such as lung cancer (e.g. in men in Northern Europe and North America) and cervical cancer (e.g. in most regions apart from Sub-Saharan Africa). However, the new data show that most countries are still faced with an increase in the absolute number of cases being diagnosed and requiring treatment and care.

SOUNDBITE (English) Dr Etienne Krug, Director, Department of Noncommunicable Diseases, Disability, Violence and Injury Prevention, WHO:
"WHO is scaling up its response to cancer, the Director-General just announced an initiative to eliminate cervical cancer which can be done through vaccination as well as improved detection and treatment. We’re also working to scale up our response to childhood cancer, we are supporting countries in cancer registries and national plans. We are advocating for more attention and we are preparing for the high-level meeting on noncommunicable diseases, which will take place in New York on the 27th September, talking about cancer but also about cardio vascular disease, diabetes and respiratory diseases and basically calling on heads of states to take on a leading role to tackle what is the most prominent public health problem of this century."

Global patterns show that for men and women combined, nearly half of the new cases and more than half of the cancer deaths worldwide in 2018 are estimated to occur in Asia, in part because the region has nearly 60% of the global population.

Europe accounts for 23.4% of the global cancer cases and 20.3% of the cancer deaths, although it has only 9.0% of the global population. The Americas have 13.3% of the global population and account for 21.0% of incidence and 14.4% of mortality worldwide. In contrast to other world regions, the proportions of cancer deaths in Asia and in Africa (57.3% and 7.3%, respectively) are higher than the proportions of incident cases (48.4% and 5.8%, respectively), because these regions have a higher frequency of certain cancer types associated with poorer prognosis and higher mortality rates, in addition to limited access to timely diagnosis and treatment in many countries.

Cancers of the lung, female breast, and colorectum are the top three cancer types in terms of incidence, and are ranked within the top five in terms of mortality (first, fifth, and second, respectively). Together, these three cancer types are responsible for one third of the cancer incidence and mortality burden worldwide.

Cancers of the lung and female breast are the leading types worldwide in terms of the number of new cases; for each of these types, approximately 2.1 million diagnoses are estimated in 2018, contributing about 11.6% of the total cancer incidence burden. Colorectal cancer (1.8 million cases, 10.2% of the total) is the third most commonly diagnosed cancer, prostate cancer is the fourth (1.3 million cases, 7.1%), and stomach cancer is the fifth (1.0 million cases, 5.7%).

Lung cancer is also responsible for the largest number of deaths (1.8 million deaths, 18.4% of the total), because of the poor prognosis for this cancer worldwide, followed by colorectal cancer (881 000 deaths, 9.2%), stomach cancer (783 000 deaths, 8.2%), and liver cancer (782 000 deaths, 8.2%). Female breast cancer ranks as the fifth leading cause of death (627 000 deaths, 6.6%) because the prognosis is relatively favourable, at least in more developed countries.

Lung cancer is the most commonly diagnosed cancer in men (14.5% of the total cases in men and 8.4% in women) and the leading cause of cancer death in men (22.0%, i.e. about one in 5 of all cancer deaths). In men, this is followed by prostate cancer (13.5%) and colorectal cancer (10.9%) for incidence and liver cancer (10.2%) and stomach cancer (9.5%) for mortality. Breast cancer is the most commonly diagnosed cancer in women (24.2%, i.e. about one in 4 of all new cancer cases diagnosed in women worldwide are breast cancer), and the cancer is the most common in 154 of the 185 countries included in GLOBOCAN 2018. Breast cancer is also the leading cause of cancer death in women (15.0%), followed by lung cancer (13.8%) and colorectal cancer (9.5%), which are also the third and second most common types of cancer, respectively; cervical cancer ranks fourth for both incidence (6.6%) and mortality (7.5%).

Lung cancer is also a leading cause of death in both men and women and is the leading cause of cancer death in women in 28 countries. The highest incidence rates in women are seen in North America, Northern and Western Europe - notably in Denmark and The Netherlands, China, and Australia and New Zealand, with Hungary topping the list.
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